Butabarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of CYP3A4 inducers may perhaps lower sufentanil amounts and efficacy, possibly precipitating withdrawal syndrome in people who've designed physical dependence to sufentanil. Discontinuation of concomitantly made use of CYP3A4 induce... https://alexisv296nkh0.wikievia.com/user