In fact, TERT phosphorylation has become shown being essential for telomerase activation. b Effect of BETi on telomere regulation. BETi compete with acetylated histones for your binding within the BRD4 bromodomains releasing BRD4 from limited telomere, destabilizing telomere protection complicated Corporation and lowering Telomerase activity. The progressive shortening of telomere https://jq-1-in-epigenetics24679.bloggazza.com/31088007/5-simple-statements-about-jq-1-role-in-gene-regulation-explained