Pentobarbital will minimize the level or result of cortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. pentobarbital will lessen the extent or influence of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified. Induction of microsomal enzymes by this drug, may possibly shorten the 50 percent-life of do... https://charlies963def8.wikicarrier.com/user